Meta analysis of continuous aspiration of subglottic secretions in preventing ventilator-associated pneumonia
10.3760/cma.j.issn.1672-7088.2014.29.017
- VernacularTitle:持续声门下吸引预防呼吸机相关性肺炎效果的Meta分析
- Author:
Juan FANG
;
Yulian LIANG
;
Jinlan YAO
- Publication Type:Journal Article
- Keywords:
Continuous aspiration of subglottic secretions;
Ventilator-associated pneumonia;
Meta-analysis
- From:
Chinese Journal of Practical Nursing
2014;30(29):54-58
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the effectiveness of continuous aspiration of subglottic secretions (CASS)in preventing ventilator-associated pneumonia.Methods The relevant randomized controlled trials were searched in the Cochrane Library,Pubmed,CNKI,VIP and Wanfang databases.The experimental group received CASS and the control group did not(NASS group).Two reviewers selected studies according to the inclusion and exclusion criteria,the quality of studies was critically appraised and data were extracted by two reviewers independently.Meta-analysis was conducted by using RevMan 5.2.Results Sixteen randomized controlled trials met the inclusion criteria and enrolled 2 576 patients.According to the meta analysis,compared with NASS,CASS reduced the incidence of ventilator-associated pneumonia,shortened the length of stay in the intensive care unit and the duration of mechanical ventilation.There was no effect on hospital mortality.Conclusions Continuous aspiration of subglottic secretions appears effective in preventing ventilator-associated pneumonia,decreasing the duration of intensive care unit length of stay and mechanical ventilation among critically ill patients with mechanical ventilation.
