Hormone Receptor-negative Metastatic Breast Cancer Presented as Cancer from an Unknown Primary Site.
10.3904/kjm.2015.89.6.728
- Author:
Hwan Il KIM
1
;
Kang Won LEE
;
Eun Sang YU
;
Hong Jun KIM
;
Ji Young SONG
;
Ji Ho JEON
;
Jae Hong SEO
Author Information
1. Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. cancer@korea.ac.kr
- Publication Type:Case Report
- Keywords:
Carcinoma, Ductal;
Breast neoplasm;
HER-2 (c-erbB-2 gene over expression) positive;
Unkonwn primary neoplasm
- MeSH:
Adenocarcinoma;
Adult;
Biopsy;
Breast Neoplasms*;
Breast*;
Carcinoma, Ductal;
Drug Therapy;
Estrogens;
Female;
Humans;
Lymph Nodes;
Lymphatic Diseases;
Receptors, Progesterone
- From:Korean Journal of Medicine
2015;89(6):728-732
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 37-year-old woman was admitted to our hospital because of cervical and axillary lymphadenopathy that developed after delivery. An axillary lymph node biopsy revealed metastatic adenocarcinoma. Immunohistochemical staining indicated that the tumor cells expressed c-ErbB-2, but were negative for the estrogen and progesterone receptors. No definite evidence of breast cancer was detected. The patient underwent chemotherapy for suspected metastatic breast cancer. She complained of swelling in the left breast 22 months later, and a biopsy showed invasive ductal carcinoma. Here, we report a case of hormone receptor-negative occult breast cancer in a patient with cervical and axillary lymphadenopathy presenting as a cancer with an unknown primary site.
