Efficacy of ambroxol combined with penehyclidine hydrochloride for prevention of pulmonary complications after surgery due to acute abdomen in pediatric patients with upper respiratory tract infection
10.3760/cma.j.issn.0254-1416.2014.10.002
- VernacularTitle:氨溴索复合盐酸戊乙奎醚预防上呼吸道感染患儿急腹症手术后肺部并发症的效果
- Author:
Bing XUN
;
Yaoming JIANG
;
Yanmin ZHANG
;
Bin CHEN
;
Min SUN
- Publication Type:Journal Article
- Keywords:
Ambroxol;
Cholinergic antagonists;
Respiratory tract infections;
Postoperative complications;
Abdomen,acute;
Child
- From:
Chinese Journal of Anesthesiology
2014;34(10):1168-1170
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy of ambroxol combined with penehyclidine hydrochloride for prevention of pulmonary complications after surgery due to acute abdomen in pediatric patients with upper respiratory tract infection.Methods Fifty pediatric patients with acute abdomen complicated with respiratory infection,of ASA physical status Ⅰ or Ⅱ,aged 6 months-5 yr,were randomly divided into test group (group A) and control group (group B),with 25 cases in each group.Immediately after admission to the operating room,ambroxol 1 mg/kg and penehyclidine hydrochloride 0.02 mg/kg were injected intravenously in group A,and atropine 0.02 mg/kg was given in group B.Extubation time and development of laryngospasm,bronchospasm and hypoxemia were recorded.The patients were followed up for 72 h after surgery and the development of postoperative pulmonary complications was recorded.Results Compared with group B,the incidence of hypoxemia and pulmonary complications was significantly decreased,and extubation time was shortened in group A.Conclusion Ambroxol combined with penehyclidine hydrochloride can prevent pulmonary complications after surgery due to acute abdomen and is helpful for prognosis in pediatric patients with upper respiratory tract infection.
