Cryptococcal Meningoencephalitis in a Systemic Lupus Erythematosus Patient without Immunosuppressants.
10.3904/kjm.2015.89.6.742
- Author:
Soo Ya BAE
1
;
Jeong Yeon KIM
;
Hyun Ho OH
;
Seong Jin CHOI
;
Jong Ho LEE
;
Moon PARK
;
Seong Hoon HAN
Author Information
1. Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea. shan@paik.ac.kr
- Publication Type:Case Report
- Keywords:
Cryptococcosis;
Meningitis, Cryptococcal;
Lupus erythematosus, Systemic
- MeSH:
Central Nervous System;
Cryptococcosis;
Diagnosis;
Humans;
Immunosuppressive Agents*;
Lupus Erythematosus, Systemic*;
Meningitis, Cryptococcal;
Meningoencephalitis*;
Mortality;
Opportunistic Infections;
Steroids
- From:Korean Journal of Medicine
2015;89(6):742-745
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cryptococcosis is an opportunistic infection that generally occurs in patients with cell-mediated immune dysfunction and involves the central nervous system. Infection is a major cause of morbidity and mortality in systemic lupus erythematosus (SLE) patients because of its innate immune dysfunction along with the administration of steroids and immunosuppressants. However, central nervous system cryptococcosis has rarely been reported in SLE patients. A timely diagnosis is critical because of its significant mortality and morbidity. Most cases of cryptococcal meningitis in SLE patients have been reported in those treated with steroids or immunosuppressants. We report on a SLE patient not on medication, who was diagnosed with cryptococcal meningoencephalitis.
