Effect and safety of primary percutaneous coronary intervention on acute ST-segment elevation myocardial infarction in elderly patients
10.3760/cma.j.issn.0254-9026.2015.02.004
- VernacularTitle:直接经皮冠状动脉内介入治疗老年急性心肌梗死患者疗效和安全性的研究
- Author:
Shenwen FU
;
Xianqing HU
;
Ming ZHONG
;
Biao TANG
;
Yanyan MAO
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Angioplasty,transluminal,Percutaneous cornary
- From:
Chinese Journal of Geriatrics
2015;34(2):126-128
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect and safety of primary percutaneous coronary intervention (PCI) of acute ST-segment elevation myocardial infarction (STEMI) in elderly patients.Methods 103 consecutive patients with STEMI treated by primary PCI were divided into two groups according to the age:the elderly group [aged≥65 years,with a mean age of (75.7 ±6.2) years(n =49],the non-elderly group [aged＜65 years,with a mean age of (43.0±8.6) years(n =54].Clinical characteristics,complications related to PCI procedure and success rate were analyzed,and major cardiovascular events (MACE) were followed up for(5.7 ± 1.2) months.Results The proportion of female,patients with Killip ≥ Ⅲ,three vessels disease and higher level of serum brain natriuretic peptide were higher in elderly group than in non-elderly group (all P＜0.05).No significant difference was observed between the two groups in success rate and complications of PCI procedure (both P＞0.05).Patients were followed up for (5.7± 1.2) months.The in-hospital and one-month mortalities were higher in elderly group than in non-elderly group [8.2％ (4 cases)vs.0％ (0 case),10.2％(5 cases) vs.0 ％ (0 case),respectively,all P＜0.05].There was no significant difference in six-month mortality and MACE between the two groups.Multivariate logistic regression analysis showed that Killip ≥ Ⅲ was related with the increase of one-month mortality in patients with STEMI undergoing primary PCI,whereas age was not.Conclusions Primary PCI is effective and safe in elderly patients with STEMI.
