Efficacy of platelet-rich plasma gel in the treatment of stage Ⅳ pressure ulcer

VernacularTitle:自体富含血小板血浆凝胶治疗Ⅳ期褥疮探讨
Author: Guoyou ZOU ; Minqian ZHENG ; Weitao JIA ; Xiaozu XU ; Jun YIN ; Dongliang WANG
Publication Type:Journal Article
Keywords: Blood platelets; Gels; Pressure ulcer; Infection
From: Chinese Journal of Geriatrics 2014;33(12):1338-1340
CountryChina
Language:Chinese
Abstract: Objective To observe the effects of platelet-rich plasma (PRP) gel in the treatment of [Ⅳ stage pressure ulcers.Methods A total of 12 patients with stage Ⅳ pressure ulcers were treated with PRP gel from December 2012 to December 2013 in our department.The PRP gel was formed by autologous PRP mixed with thrombin and calcium chloride.The PRP gel was applied to the wound after dressing.Time intervals between dressing were 4 days.Overall pressure ulcer improvement was assessed every week until complete wound healing.Results All stage Ⅳ pressure ulcer wound infection was controlled and fresh granulation tissue was found after 2 times of PRP gel covering.The time of ulcer wound healing were 6-10 weeks (mean 8 weeks).The times of changing the PRP gel were 16.No patients experienced adverse reactions during treatment.Conclusions PRP gel can effectively control the pressure ulcer infection and promote ulcer wound healing.