Predictive value of fracture risk assessment tool for determining fracture probabilities in middle aged and elderly patients with type 2 diabetes
10.3760/cma.j.issn.0254-9026.2015.02.016
- VernacularTitle:骨折风险评估工具(FRAX)对中老年2型糖尿病患者骨折风险的预测价值
- Author:
Xiaopei CHEN
;
Tianfeng WU
;
Hexin ZHENG
;
Fang YUAN
;
Xiaolin WEN
;
Haibao XIE
- Publication Type:Journal Article
- Keywords:
Fractures,bone;
Risk assessment;
Bone density;
Diabetes mellitus,type 2
- From:
Chinese Journal of Geriatrics
2015;34(2):168-170
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the predictive value of fracture risk assessment tool (FRAX) for determining fracture probabilities in middle-aged and elderly patients with type 2 diabetes.Methods Retrospective analysis was carried out on 153 type 2 diabetic patients aged over 50 years undergoing dual energy X-ray absorptiometry measurements.Fracture risk factors including age,gender,height,weight,body mass index,history of previous fragility fractures,parental history of hip fracture,history of smoking,excessive drinking,long-term use of steroid hormone,history of rheumatoid arthritis,the history of secondary osteoporosis diseases,and femoral neck T-score of bone mineral density (BMD) were recorded.FRAX scores with BMD (FRAX/BMD) and without BMD (FRAX/-) were calculated.Therapeutic interventions were recommended if the 10-year risk of fractures was more than 3％ for hip osteoporotic fractures and more than 20％ for other major fractures.Subjects were separated into the identical treatment recommendation group and the different treatment recommendation.Fracture risk factors were compared between groups.Results 133 (6.9 ％) patients had identical fracture risk predictions in the FRAX calculation,regardless of whether BMD join in or not.Age,gender and femoral neck T scores had significant differences between the two groups (all P＜0.001),while other risk factors had no statistical differences between the two groups (all P＞0.05).Conclusions In most middle-aged and elderly patients with type 2 diabetes,the FRAX/-provides the same prediction as FRAX/BMD value for predicting fracture risk,which shows that fracture risks can be predicted without bone density examination.The FRAX/-has higher predictive values on fracture for people who are younger,male,and has higher BMD.
