Effects of general anesthesia on postoperative cognitive function in elderly orthopedic patients
10.3760/cma.j.issn.1008-6315.2015.06.021
- VernacularTitle:全身麻醉对骨科老年患者术后认知功能的影响
- Author:
Chuanqi FANG
- Publication Type:Journal Article
- Keywords:
General anesthesia;
Elderly orthopedic patients;
Cognitive function
- From:
Clinical Medicine of China
2015;31(6):550-552
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of general anesthesia for postoperative cognitive function in elderly orthopedic patients.Methods Elderly patients with orthopedic patients in the First People's Hospital of Shangqiu from June 2010 to September 2013 were randomly divided into general anesthesia group(n=74) and epidural group(n=74),and the cognitive functions of patients were observed by the minimum mental status examination(MMSE) score before and after treatment.Results The differences between the heart rate (HR),mean arterial pressure (MAP),pulse Oxygen Saturation (SpO2) and surgical observation indicators in both groups were not statistically significant(P＞0.05).MMSE score in general anesthesia group and epidural group decreased significantly at day 1((18.4± 1.6) point,(21.2± 2.5) point) and day 7 ((20.5± 2.3) point,(23.4 ±2.1) point) after treatment than before treatment ((24.4±2.2) point,(24.5±2.1) point;F inner group =13.56,P＜0.01;F between group=12.46,P＜0.01;F across group=11.80,P＜0.01).The incidence rates of POCD scores in the epidural group were lower than those in the general anesthesia group.But the difference was not statistically significant (P＞0.05).Conclusion Both general anesthesia and epidural anesthesia impacts on cognitive function in elderly patients after orthopedic surgery,but the impact of general anesthesia is greater.
