Therapeutic effects of Flupentixol and Melitracen with conventional medicine on functional gastrointestinal disease for officers and soldiers
10.3760/cma.j.issn.1008-6315.2015.01.015
- VernacularTitle:氟哌噻吨美利曲辛联合常规药物治疗官兵功能性胃肠病效果分析
- Author:
Xiaorong REN
;
Yugui CAO
;
Weitao CAI
;
Zhijing CUI
- Publication Type:Journal Article
- Keywords:
Functional gastrointestinal disease;
Flupentixol and melitracen;
Anxiety;
Depression
- From:
Clinical Medicine of China
2015;31(1):47-50
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the therapeutic effects of Flupentixol and Melitracen with conventional medicine on functional gastrointestinal disease of officers and soldiers.Methods Eighty-two officers and soldiers with functional gastrointestinal disease which defined by the Rome Ⅲ were randomly divided into two groups.The cases in therapy group were treated with Flupentixol and Melitracen combined with conventional medicine,and the cases in control group were simply treated with conventional medicine.The scales changes of clinical eddicacy,sympotoms,depression,anxiety amd the quality of life at the beginning and 8 weeks 'treatment were recorded.Results All offers and soldiers completed the therapy,and the overall response rate was 92.68％ in the therapy group and 70.13％ in the control group(x2 =6.61,P ＜0.05).The general severity score of symptoms,the score of depression and the score of anxiety in the therapy group after treatment were significantly lower than that of before treatment (t =27.76,16.24,16.28 ; P ＜ 0.05),while there were no significant difference in the control group(P ＞ 0.05).The score of the quality of life in the therapy group (SF-36) after treatment was improved significantly than that of before treatment (P ＜ 0.05),and the difference of two group was significant (P ＞ 0.05).Conclusion The therapy scheme of Flupentixol and Melitracen with conventional medicine on offiers and soldiers with functional gastrointestinal disease can improve the total effective rate,clinical symptoms,depression,anxiety and the quality of life.
