Risk factors of cardiorenal syndrome type 1 in patients with acute myocardial infarction
10.3760/cma.j.issn.1008-1372.2015.05.016
- VernacularTitle:急性心肌梗死并发1型心肾综合征危险因素分析
- Author:
Xiang PENG
;
Jie FENG
;
Jianqiang PENG
;
Ying GUO
- Publication Type:Journal Article
- Keywords:
Myocardial infarction/CO;
Heart failure/CO;
Kidney failure/CO;
Syndrome;
Risk factors
- From:
Journal of Chinese Physician
2015;17(5):695-698
- CountryChina
- Language:Chinese
-
Abstract:
Objectives To investigate the risk factors of cardiorenal syndrome type 1 (CRS1) in patients with acute myocardial infarction (AMI).Methods The medical date of hospitalized patients with AMI from January,2013 to February,2014 in Hunan Provincial People~ Hospital were reviewed.A total of 265 patients with AMI was divided into CRS1 and non-CRS1 groups.The univariate comparison and multivariate Logistic regression analysis were performed to obtain the CRS1 risk factors.Results In the 265 AMI patients,CRS1 was found in 59 patients (22.3%).Age,history of diabetes,Killip classification,left ventricular ejection fraction (LVFF),baseline serum creatinine,blood urea nitrogen,uric acid,baseline evaluated glomerular filtration rate (eGFR),serum sodium,the left anterior descending artery lesion,emergency percutaneous coronary intervention (PCI),β-blocker,and angiotensin converting enzyme inhibitor/angiotensin receptor antagonist (ACEI/ARB) were statistically different between CRS1 and non-CRS1 groups (all P < 0.05).Multivariate logistic regression showed that age,history of diabetes,Killip classification,reduced LVEF,reduced eGFR,hyponatremia,the left anterior descending artery lesionn,emergency PCI non-undergo,and β-blocker non-use were independent risk factors for CRS1 after AMI.Conclusions CRS1 is a common complication in AMI patients,which is associated with many factors.Our data suggest that patients with AMI should be more comprehensively assessed and monitored,thereby preventing the occurrence of CRS1.