The relationship between depression and C reactive protein in patients with chronic ischemic heart failure

VernacularTitle:抑郁与慢性缺血性心力衰竭患者C反应蛋白的关系
Author: Yong WANG ; Ming LIU ; Fangfang HU ; Yanbo WAN
Publication Type:Journal Article
Keywords: Depression; Ischemic cardiomyopathy; Heart failure,chronic; C reactive protein
From: Chinese Journal of Behavioral Medicine and Brain Science 2015;24(4):353-355
CountryChina
Language:Chinese
Abstract: Objective To determine the influence of depression on C reactive protein in patients with chronic ischemic heart failure (CIHF).Methods 73 patients with CIHF were divided into CIHF without depression group(n=49) and CIHF with depression group (n=24) according to the standard sore of the self-rating depression scale.C reactive protein(CRP)and other clinical characteristics were detected.The geometric means of CRP between two groups were compared,and stepwise multiple linear regression analysis was used to confirm the independent correlation factors of CRP.Results (1) The geometric means of CRP in CIHF without depression group and CIHF with depression group were (1.38± 1.29)mg/L and (1.78±1.53) mg/L respectively.No statistically significant difference was found between two groups(P=0.276).(2) Stepwise multiple linear regression analysis showed that aspirin inversely related with CRP(β=-1.070,P=0.004),but brain natriuretic peptide (BNP)positively related with CRP(β=0.426,P=0.001).Conclusion Depression has no additional effect on CRP in patients with CIHF.