The effect of minimally invasive thoracoscopic left atrial appendage excision on ANP secretion in atrila fibrillation patients
10.3760/cma.j.issn.1001-4497.2014.10.009
- VernacularTitle:房颤患者胸腔镜下射频消融并左心耳切除对ANP分泌的影响
- Author:
Zhenhua ZHANG
;
Haibo ZHANG
;
Xu MENG
;
Jie HAN
;
Yan LI
;
Gang WANG
- Publication Type:Journal Article
- Keywords:
Atrial appendage;
Atrial natriuretic factor;
Atrial fibrillation;
Surgical procedures,minimally invasive
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2014;30(10):603-605
- CountryChina
- Language:Chinese
-
Abstract:
Objective The aim of the present study was to monitor the plasma levels of atrial natriuretic peptide(ANP) in patients accepting minimally invasive ablation.Methods The demographic and clinical data were collected from 26 consecutive patients with paroxysmal atrial fibrillation.Two milliliter of peripheral blood was harvested before operation,7 days and 3 months post-operation followed by ANP assay using ELISA kit.The repeated measurements were performed for each sample and One-way ANOVA was used for statistical analysis.Results Before operation,the ANP levels in plasma was (2.86 ± 1.47) pg/ml.No significant changes of this ANP levels were observed 7 days and 3 months after operation,which were(2.83 ± 1.08) pg/ml and(2.75 ±0.87) pg/ml,respectively.The Pvalue of sphericity Mauchly test was 0.008 for repeated measurements and for correction coefficient,P =0.801.Conclusion These findings suggest that the minimally invasive ablation and left appendage excision in patients with atrial fibrillation has no significant effect on atrial ANP secretion.
