Effects of acute normovolemic hemodilution used in coronary artery bypass graft surgery

VernacularTitle:单纯CABG术中应用急性等容血液稀释自体输血效果评价
Author: Huaibin WANG ; Wenjun ZHEN ; Xiaokang OUYANG ; Yujian MA ; Jie TAN ; Wenqi LUO
Publication Type:Journal Article
Keywords: Cardiopulmonary bypass; Blood transfusion,autologous; Acute normovolemic hemodilution
From: Chinese Journal of Thoracic and Cardiovascular Surgery 2015;31(4):230-232
CountryChina
Language:Chinese
Abstract: Objective To investigate effects of acute normovolemic hemodilution(ANH) used in on-pump coronary artery bypass graft(CABG) surgery.Methods 60 patients had received CABG surgery under cardiopulmonary bypass,of which 30 patients using ANH techniques and 30 patients using no ANH techniques.A series of index were observed and compared between the two groups after operation.Results All patients had been revascularized completely with stable surgical procedure,no serious complications,no operative mortality.Oxygen supplying was balanced with demanding,without tissue hypoxia.Indicators of myocardial protective effect,coagulation,kidney function,degree of systemic inflammatory reaction and postoperative drainage volume were not significantly different between the two groups(P ＞ 0.05).Allogeneic blood transfusion volume of the study group was significantly lower than that of the control group [(1.1 ± 0.8) U vs.(2.3 ± 1.1) U,P ＜ 0.05].Condusion The ANH technique used in CABG operation on appropriate patient is feasible and safe,with satisfactory clinical result.