Experimental study of changes in arteriovenous pressure difference on the survival area of reverse island flap
10.3760/cma.j.issn.1001-2036.2015.02.011
- VernacularTitle:改变动静脉压力差对逆行岛状皮瓣成活面积的影响
- Author:
Peiji WANG
;
Jupu ZHOU
;
Bo JIANG
;
Jiaju ZHAO
;
Yong ZHANG
- Publication Type:Journal Article
- Keywords:
Reverse-flow island flaps;
Pressurization;
Venous drainage;
Survival rate
- From:
Chinese Journal of Microsurgery
2015;38(2):144-148
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of changing the arteriovenous pressure difference on the survival area of reverse island flap in New Zealand white rabbits models.Methods The saphenous artery and saphenous vein of New Zealand rabbits were selected to design experimental models of reverse island flap.Experi mental rabbits were randomly divided into 4 groups:group A:control group (reserved pedicle integrity of superficial veins);group B:part anastomosis of saphenous artery group (the distal saphenous artery of the flap was cut,then trimmed its original diameter to half and done end-to-end anastomosis);group C:part anastomosis of vein group (distal superficial veins was cut,then trimmed its original diameter to half and done end-to-end anastomosis);group D:ligated superficial veins group (pedicle superficial veins was ligated).After surgery,the flaps were measured by general observation.Blood distribution at different times of the flaps was detected by radionuclide scans.Survival area of the flap was measured to compare the survival rate of flap.Distribution of blood vessels and the state of blood cells were observed by Histological examination.Results The flap survival rate was (82.27-± 11.71)％ in group B,showing significant differences when compared with that group A (47.70-± 11.18)％,group C (47.70 ± 11.18)％ and group D (47.70 ± 11.18)％ (P ＜ 0.05).Radionuclide scans showed that the radioactive material in group B could be seen clearly,the radioactive material in groups A,C and D were a transient existence.Ten days postoperatively,histological observation showed that group B had more capillary regeneration and blood cells remain compared with other groups.Conclusion Increase the blood supply can increase the survival area of the reverse island flap,and simply promote the venous drainage can not effectively improve the survival rate of the flap.
