A Case of Idiopathic Thrombocytopenic Purpura with Anti-E Antibody Developed after Transfusion of Platelet Concentrates.
- Author:
Kyeong Hee KIM
1
;
Kyong Eun KIM
;
Jin Yeong HAN
;
Jeong Man KIM
;
Jae Ho YOO
Author Information
1. Department of Laboratory Medicine, Dong-A University College of Medicine, Busan, Korea. progreen@dau.ac.kr
- Publication Type:Case Report
- Keywords:
Alloantibody;
Anti-E antibody;
Platelet transfusion;
Anti-D immunoglobulin
- MeSH:
Blood Platelets*;
Humans;
Immunoglobulins;
Infant;
Isoantibodies;
Male;
Platelet Transfusion;
Purpura, Thrombocytopenic, Idiopathic*
- From:Korean Journal of Blood Transfusion
2005;16(2):255-260
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Alloantibodies against RBCs after transfusion of only platelet products are rarely reported except for RhD mismatched platelet transfusion. We report a case of anti-E antibody developed after transfusion of platelet concentrates. The patient was a 27- month male infant with idiopathic thrombocytopenic purpura and was treated with IV immunoglobulin and IV Rh immunoglobulin. Anti-E antibody was detected after transfusion of 18 units of platelet concentrates for about 40 days. RBC alloimmunization was developed after transfusion of platelet products, which suggests platelet transfusion may be cause of RBC alloimmunization in childhood.
