The effect of different doses of simethicone on colonoscopy bowel preparation

VernacularTitle:不同剂量西甲硅油行结肠镜检查术前肠道准备的效果分析
Author: Haiyan TAO ; Peng LI ; Shutian ZHANG
Publication Type:Journal Article
Keywords: Colonoscopy; Premedication; Simethicone; Polyethylene glycols
From: Chinese Journal of Digestive Endoscopy 2014;31(10):579-582
CountryChina
Language:Chinese
Abstract: Objective To observe the clinical effect of different doses of simethicone on the colonoscopy bowel preparation.Methods One hundred and fifty outpatients who received colonoscopy were randomly divided into three groups:group A1 (PEG plus 5 ml simethicone),group A2 (PEG plus 10 ml simethicone) and group B (PEG =polyethylene glycol electrolyte).The colonic cleaness,effect of removing bubbles,total procedure time,patients' satisfaction and tolerance were observed during the examination.Results The satisfaction with bubbles removal were 98.0％ (49/50),100.0％ (50/50) and 80.0％ (40/50) with significant difference(x2 =17.855,P =0.000).However,there was no difference in cleaness (x2 =1.500,P =0.472),total procedure time (Z =-0.333,P =0.765),patients' satisfaction (x2 =6.303,P =0.178) and tolerance (x2 =8.238,P =0.083).Conclusion Simethicone is of benefit for colonoscopic bowel preparation in removing air bubbles,which can enhance visibility.Five ml dose of simethicone can meet the basic need of removing air bubbles,and 10 ml dose of simethicone can exert better effects.