Evaluation of susceptibility weighted imaging in defining penumbra during acute stage of cerebral infarction and comparison with perfusion weighted imaging
10.3760/cma.j.issn.1006-7876.2014.10.009
- VernacularTitle:磁敏感加权成像界定卒中急性期缺血半暗带及与灌注加权成像的对照研究
- Author:
Song LUO
;
Fang DENG
;
Ying ZHANG
;
Jing MIAO
;
Ying CHEN
;
Lijuan WANG
;
Jiachun FENG
- Publication Type:Journal Article
- Keywords:
Stroke;
Brain ischemia;
Magnetic resonance imaging;
Diffusion magnetic resonance imaging
- From:
Chinese Journal of Neurology
2014;47(10):711-715
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate whether susceptibility weighted imaging (SWI) can be used in definition of penumbra during acute stage of cerebral infarction,compared with perfusion weighted imaging (PWI).Methods Ischemic stroke patients within 3 days after onset were included.They adopted multimodal magnetic resonance imaging examination,including regular magnetic resonance imaging sequence (T1 WI,T2 WI and T2-weight fast fluid-attenuated inversion-recovery),diffusion weighted imaging (DWI),PWI and SWI.Alberta Stroke Programme Early CT Score was done on DWI,SWI and PWI.The mismatch of SWI-DWI (minimal indensity projection (mIP)-DWI) was compared with that of PWI-DWI (mean transit time (MTT)-DWI) and analyzed statistically.The application of prominent vein (PV) on SWI as a sort of alternation of cerebral blood volume (CBV) and direct observation of thrombosis in arteries on SWI were done.Results The SWI-DWI (2.39 ± 1.42) and the MTT-DWI (2.72 ± 1.49) mismatch showed no statistically significant difference (r =0.726,P ＞ 0.05).The grade of PV was positively related with the CBV of the ipsilateral brain tissue on admission (r =0.564,P ＜ 0.05).SWI showed the similar ability with magnetic resonance angiography to judge responsible blood vessels with susceptibility vessel sign.Conclusion SWI-DWI can evaluate the ischemic penumbra.PV may reflect the increased blood volume of the lesion side of the brain tissue.SWI can reveal the thrombosis of the responsible vessels.
