Efficacies of fluid resuscitation plus continuous veno-venous hemofiltration in the treatment of septic shock
10.3760/cma.j.issn.1671-7368.2015.01.014
- VernacularTitle:容量复苏联合连续静脉血滤治疗脓毒性休克的疗效观察
- Author:
Chunli ZHAO
;
Zhiyang DONG
;
Yang HE
;
Shuting LIU
;
Ying LIU
;
Chun LI
- Publication Type:Journal Article
- Keywords:
Shock,sepsis;
Continuous veno-venous hemofiltration
- From:
Chinese Journal of General Practitioners
2015;14(1):47-50
- CountryChina
- Language:Chinese
-
Abstract:
A total of 58 patients with simple septic shock were recruited from intensive care unit and divided into control group (n =28) and treatment group (n =30) according to treatment modalities.The control group was routinely treated.The treatment group received continuous veno-venous hemofiltration (CVVH) for 10-14 days plus routine measures.After 3 days,the score of acute physiology and chronic health evaluation-Ⅱ (APACHE-Ⅱ) of the treatment group was better than that of the control group (P ＜ 0.01).And sequential organ failure assessment (SOFA),left ventricular end diastolic diameter (LVEDD),left ventricular end systolic diameter (LVEDS) and left ventricular ejection fraction (LVEF) improved significantly (P ＜ 0.05).And the relevant blood biochemical parameters improved significantly better than the control group (P ＜ 0.05).In the group CVVH,there were mortality (n =7,23％) and multiple organ failure (MODS) (n =6,20％) ; In the control group,mortality (n =14,50％) and MODS (n =13,46％).The mortality rate had inter-group differences of statistical significance (x2 =4.38,P ＜0.05).Thus early volume resuscitation plus CVVH had excellent curative efficacies for septic shock.
