Incidence and risk factors of spontaneous hemorrhagic transformation in cardioembolism and large artery atherosclerotic infarction
10.3760/cma.j.issn.1671-7368.2014.10.020
- VernacularTitle:心源性脑栓塞和大动脉粥样硬化性脑梗死患者自发性出血性转化的发生及相关因素分析
- Author:
Meijuan XIAO
;
Weiyong YIN
;
Zusen YE
;
Yungang CAO
;
Bei SHAO
;
Zhao HAN
- Publication Type:Journal Article
- Keywords:
Cerebral infarction;
Spontaneous hemorrhagic transformation;
Risk factors
- From:
Chinese Journal of General Practitioners
2014;13(10):848-850
- CountryChina
- Language:Chinese
-
Abstract:
To explore the incidence and risk factors for spontaneous hemorrhagic transformation (HT) of cardioembolism (CE,n =150) and large artery atherosclerotic infarction (LAA,n =370).The incidence of HT was 29.3% in CE.And it was significantly higher than 9.7% (P <0.05).Infarct size,low-density lipoprotein-cholesterol (LDL-C) and admission National Institutes of Health Stroke Scale (NIHSS) score were independent predictors of spontaneous hemorrhagic transformation in LAA.OR values were 3.92,2.96 and 1.45 respectively.Infarct size,admission NIHSS score and random blood glucose level were independent predictors of spontaneous hemorrhagic transformation in CE.OR values were 4.86,2.42 and 1.42 respectively.As compared with LAA,CE was more prone to HT.LAA and CE-related factors of hemorrhagic transformation are not completely identical.