Rectal carcinoid: clinical analysis of 21 cases
10.3760/cma.j.issn.1671-7368.2014.12.012
- VernacularTitle:直肠类癌21例的临床特点及随访分析
- Author:
Tian LI
;
Qian LIU
;
Yi FANG
;
Xiaohong MENG
;
Mingfang JI
;
Lu XIA
- Publication Type:Journal Article
- Keywords:
Rectal neoplasms;
Carcinoid tumor;
Clinical analysis
- From:
Chinese Journal of General Practitioners
2014;13(12):995-998
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical characteristics,pathological classification and therapy strategy of rectal carcinoid and its prognostic factors.Methods Forty four patients with rectal carcinoid were diagnosed and treated in Ruijin Hospital Shanghai Jiaotong University from January 2006 to November 2013,among whom 21 patients (19 males and 2 females) were followed-up for 1-7.5 years.The clinical data of these cases were retrospectively analyzed.Results The patients underwent colonoscopy because of changed bowel habits and/or abnormal digital rectal examination,none of them had carcinoid syndrome.Colonoscopy showed that most lesions presented yellowish in color and smooth in surface; the diameter of the tumor was ≤ 1.0 cm in 12 cases (57％) ; the tumors were located at the rectum within 8 cm from anal rim in 17cases (76％); most of them were well differentiated.Immunohistochemistry demonstrated that NSE expression was highly positive.The 1 year-and 3year-survival rate were both 100％.Among 8 cases who were followed up for over 5 year,2 relapsed.Conclusions The digital rectal examination plays a key role in detecting rectal carcinoid.Though prognosis is relatively good,we should keep close following-up to detect the recurrence.The main risk factors influencing the prognosis are tumor size,depth of invasion and clinical stage.The combination measurement of CEA,TSGF,CA19-9 and NSE will either increase the sensitivity or the specificity of early detection.
