Surgical treatment of simultaneous pancreas-kidney transplantation: causes and outcomes
10.3760/cma.j.issn.0254-1785.2014.12.005
- VernacularTitle:胰肾联合移植后并发症外科治疗的临床分析
- Author:
Jianming ZHENG
;
Wenli SONG
;
Jinpeng TU
;
Chunbai MO
;
Zhongyang SHEN
- Publication Type:Journal Article
- Keywords:
Kidney transplantation;
Pancreas transplantation;
Combined transplantation;
Surgical complication;
Diabetes;
Surgical treatment
- From:
Chinese Journal of Organ Transplantation
2014;35(12):724-727
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the complications,treatments and prognosis of simultaneous pancreas-kidney transplantation,especially on surgical complications and treatments.Method The causes and outcomes of surgical treatment in 70 cases of simultaneous pancreas-kidney transplantation performed between Dec.1999 and June 2012 were retrospectively analyzed in our center.Result Sixteen patients (22.9％) underwent one or more reoperations.The causes for reoperation were as follows:2 cases of hematuria,4 cases of abdominal hemorrhage,4 cases of abdominal infection,4cases of pancreatic thrombosis,2 cases of renal graft's artery rupture,1 case of renal allograft rupture,1 case of intestinal fistula,and 1 case of pancreatic fistula.Eight pancreas grafts were lost in the first year.Pancreatectomy was performed on the other 5 cases:4 cases of pancreatic thrombosis,1 case of intestinal fistula,accounting for 43.8％ of the patients subject to reoperation.The recipients,kidney,pancreas survival rate in reoperation group at 1 year was 87.5％,75％,and 56.3％ respectively; and that in control group at 1 year was 98.1％,98.1 ％,and 98.1 ％ respectively.There was significant difference in kidney survival rate (P＜0.01,chi-square =6.79),and pancreas survival rate (P＜0.01,chi-square =17.47) between two groups.Conclusion Although simultaneous pancreas-kidney transplantation provides a successful and effective treatment for diabetics with end-stage renal disease,surgical treatment due to complications is still an important factor in short-term survival on the grafts.
