Comparative study of liver regeneration between normal donors and recipients after fight lobe adult living donor liver transplantation
10.3760/cma.j.issn.0254-1785.2014.10.007
- VernacularTitle:成人亲属活体右半肝移植术后供、受者肝再生的研究
- Author:
Qian JI
;
Zhiqiang CHU
;
Wen SHEN
;
Ji QI
- Publication Type:Journal Article
- Keywords:
Living donor liver transplantation;
Tomography,X-ray computed;
Volumetric measurement;
Liver regeneration
- From:
Chinese Journal of Organ Transplantation
2014;35(10):603-606
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate and compare liver regeneration between normal donors and recipients at the different stages after right lobe adult living donor liver transplantation (LDLT) using MSCT.Method Sixty-eight living donors and 63 recipients without complications were included in this study.We did CT volumetric measurement of the liver by using IQQA-Liver workstation.The relationship between graft volume measured by preoperative MSCT and intraoperative actual graft volume was evaluated.The liver regenerative ratio at different stages of donors and recipients after LDLT was calculated and compared.Result Preoperative measurement of total liver and grafts resulted in a mean volume of (1366.99 ± 234.75) cm3 (standard deviation) and (862.73 175.94) cm3 (VCT-right),respectively.Intraoperative volume of the grafts was (654.46 ± 151.23) ml (Vintraop).Corresponding pre-and intraoperative data were correlated significantly each other (r =0.795,P=0.000).Vintraop can be calculated with the equation:Vintraop =64.949 + 0.683 VCT-right.There was significantly difference in LRR between donors and recipients at 0.5,1,3 and 6 months after LDLT (P＜ 0.05).Conclusion The patterns of normal liver regeneration between donors and recipients after LDLT are different.The liver of donors regenerates more significantly and quickly than recipients.Liver volumetric measurement by using MSCT is a valid modality to evaluate liver regeneration after LDLT.
