Auxiliary partial orthotopic liver transplantation in mice
10.3760/cma.j.issn.0254-1785.2014.09.010
- VernacularTitle:小鼠辅助性原位部分肝移植模型的建立
- Author:
Qi CHENG
;
Dan GAO
;
Xin LONG
;
Xiaoping CHEN
;
Peng ZHU
- Publication Type:Journal Article
- Keywords:
Mice;
Liver transplantation;
Model;
Liver regeneration
- From:
Chinese Journal of Organ Transplantation
2014;35(9):552-554
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the technique of auxiliary partial orthotopic liver transplantation model in C57BL/6 mice.Method The donor portal vein and hepatic vein were anastomosed with Cuff and suture techniques respectively.The donor bile duct was implanted into recipient duodenum.Result The operation time of harvesting donor's liver and anhepatic phase and recipient was (30 ± 3),(6-± 1) and (58 ± 5) min respectively.The model success rate was 96％,and the 4-week survival rate was 88％.Conclusion The animal model was stable with high success-rate and can be used for the study of auxiliary partial orthotopic liver transplantation.
