Impact of postoperative complications on survival after hepatic resection for metastatic colorectal cancer patients

VernacularTitle:结直肠癌肝转移切除术后并发症对生存影响
Author: Hongwei WANG ; Kun WANG ; Quan BAO ; Yi SUN ; Kemin JIN ; Xiaoluan YAN ; Baocai XING
Publication Type:Journal Article
Keywords: Colorectal neoplasms; Neoplasms metastasis; Hepatectomy; Postoperative complications
From: Chinese Journal of General Surgery 2015;30(1):42-45
CountryChina
Language:Chinese
Abstract: Objective To evaluate the correlation between postoperative complications and prognosis after radical hepatic resection for colorectal liver metastasis (CRLM).Methods We retrospectively summarized patients' clinicopathological data and postoperative complications.Postoperative complications were graded using Dindo-Clavien system of classification.Then we investigate the relation between these data and prognosis.Results One hundred and seventy-three patients were recruited.Postoperative complications developed in 59 (34.1％) cases.37 patients had minor complications and 22 patients had major complications.On univariate (x2 =8.106,P =0.004) and multivariate analysis (x2 =8.006,P =0.005),complication was an independent predictor of overall survival (OS).However,in a subgroup of patients with minor compications,morbidity was not associated with a significant reduction in both OS (x2 =3.199,P =0.074) and disease-free survival (x2 =1.313,P =0.252).Conclusions Postoperative complications are an independent factor for long-term outcomes after hepatic resection for CRLM.