Indwelling transpulmonary artery thrombolytic therapy for acute pulmonary embolism
10.3760/cma.j.issn.1007-631X.2014.12.005
- VernacularTitle:急性肺动脉栓塞的肺动脉留置导管溶栓治疗56例经验
- Author:
Yongkang DANG
;
Liu YANG
;
Haitao ZHAO
;
Jianquan GUO
;
Yongtao BAO
- Publication Type:Journal Article
- Keywords:
Pulmonary embolism;
Thrombolytic therapy;
Vena cava filters;
Catheters,indwelling
- From:
Chinese Journal of General Surgery
2014;29(12):912-914
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate indwelling intrapulmonary artery catheter thromolysis for acute pulmonary embolism.Methods From June 2011 to June 2013 56 cases of acute pulmonary embolism were diagnosed by multi-row spiral CT and admitted at the Department of Vascular Surgery.The average age was (56 ± 11) years.Inferior vena cava filter was implanted and pulmonary angiography,catheter thrombectomy,indwelling pulmonary intraarterial thrombolytic therapy was performed.Postoperatively low molecular weight heparin and warfarin was given,dosage adjusted by prothrombin international normalized ratio at 2-3.Results Mean pulmonary arterial pressure (mPAP) decreased from (43 ± 7) mmHg to (22 ± 6) mmHg (P ＜ 0.05),arterial partial pressure of oxygen (PO2) rose from (49 ± 8) mmHg to (83 ± 9) mmHg (P ＜ 0.05).Clinical symptoms significantly relieved in 51 out of the 56 cases (91％).45 patients were followed up for an average of (15 ± 4) months,with one recurrence.There was no filter migration,vena cava thrombosis,chronic obstructive pulmonary disease and other complications.Conclusions Emergency pulmonary artery indwelling catheter thrombolysis is safe and effective therapy for acute pulmonary thromboembolism.
