Preoperative spleen-liver volume ratio predicts the risk of liver cancer recurrence after hepatectomy
10.3760/cma.j.issn.1007-631X.2015.03.002
- VernacularTitle:术前脾肝体积比可预测肝癌切除术后复发的危险性
- Author:
Genglong ZHU
;
Chaonong CAI
;
Zhidong LIN
;
Kunwei LI
;
Xiaopeng HONG
;
Dong CHEN
;
Baimeng ZHANG
- Publication Type:Journal Article
- Keywords:
Carcinoma,hepatocellular;
Neoplasm recurrence;
Hepatectomy;
Spleen-liver volume ratio
- From:
Chinese Journal of General Surgery
2015;30(3):181-184
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of preoperative spleen-liver volume ratio for predicting recurrence of primary liver cancer after hepatectomy.Methods Clinical data of 75 cases of hepatocellular carcinoma undergoing hepatectomy were analyzed retrospectively.According to the preoperative spleen-liver volume ratio,these patients were divided into 2 groups:those with spleen-liver volume ratio ＜ 0.8,and spleen-liver volume ratio≥0.8.Patients were followed-up until March 2014.Cox ratio risk pattern analysis was used for the recurrent correlative factors.Results Univariate analysis showed that preoperative AFPL3％ ≥ 10％,the maximum diameter of the tumor ＞ 5 cm,the number of tumor ＞ 3,spleen-liver volume ratio ≥0.8,vascular invasion,positive resection margin and hepatic or portal vein tumor thrombus were all risk factors of poor disease-free survival (P ＜ 0.05).Cox regression analysis revealed that spleen-liver volume ratio ≥0.8,AFP-L3％ ≥10％,the maximum diameter of the tumor ＞5 cm and hepatic or portal vein tumor thrombus were independent predictors of poor disease-free survival after hepatectomy for hepatocellular carcinoma(P ＜ 0.05).Conclusions Preoperative spleen-liver volume ratio ≥0.8 was an independent adverse predictor of poor disease-free survival.
