Clinicopathologic features and survivals of postoperative gastric carcinoma patients by different tumor locations
10.3760/cma.j.issn.1007-631X.2015.02.002
- VernacularTitle:不同部位胃癌患者的临床病理特点和预后
- Author:
Jianjun PENG
;
Kaiming WU
;
Yujie YUAN
;
Hui WU
;
Shirong CAI
;
Yulong HE
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Pathology,clinical;
Prognosis
- From:
Chinese Journal of General Surgery
2015;30(2):92-95
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarise the clinicopathologic features and survival of gastric cancer at different tumor locations.Methods A total of 942 adult gastric cancer patients undergoing curative gastrectomy with lymphadenectomy were recruited from the First Affiliated Hospital,Sun Yat-sen University,and examined retrospectively.In all cases,patients' age,gender,pTNM stage and survival time were identified and recorded.Results There were 208 carcinoma cases at gastroesophageal junction (GEJ,22.1%),261 fundus/body cases (27.7%),445 antrum/pylorus cases (47.2%) and 28 whole stomach cases (3.0%).Compared with fundus/body and antrum/pylorus carcinoma,GEJ carcinomas were more often seen in males,among older patients,with larger tumor size and deeper infiltrated tumors,higher stage and worse 5-year disease-free survivals.Whole stomach carcinoma had predilection in female,younger patients,and at later stages and worst 5-year disease-free survival.Conclusions Gastric carcinomas differ greatly in biologic behavior and prognosis by anatomic locations.GEJ carcinoma has independent biologic features.Whole stomach carcinoma is of the highest malignancy and worst prognosis.