Severe hemolytic anemia caused by passenger lymphocyte syndrome after kidney transplantation: one case report
10.3760/cma.j.issn.0254-1785.2014.11.008
- VernacularTitle:肾移植后过客淋巴细胞综合征致重度溶血性贫血一例
- Author:
Lei ZHAO
;
Lulin MA
;
Hongxian ZHANG
;
Xiaofei HOU
;
Lei LIU
- Publication Type:Journal Article
- Keywords:
Hemolytic anemia;
Passenger lymphocyte syndrome;
Kidney transplantation
- From:
Chinese Journal of Organ Transplantation
2014;35(11):672-675
- CountryChina
- Language:Chinese
-
Abstract:
Objective A kidney transplantation patient who was diagnosed with autoimmune hemolytic anemia (AIHA) caused by passenger lymphocyte syndrome (PLS) was reviewed.Method A male kidney transplantation patient aged 31 was admitted due to severe anemia.Direct antiglobulin test (DAT) was positive and reticulocyte was elevated significantly,and PLS was diagnosed.He was treated with blood transfusion,glucocorticoid and intravenous immunoglobulin,and recovered at last.Result PLS is a rare but important cause of AIHA after kidney transplantation,often occurs in blood type A patient who received a kidney from a blood type O donor.Final diagnosis depends on the detection of anti-erythrocyte antibody in recipient serum.Conclusion PLS should be considered when anemia with unknown reasons occurred in kidney transplantation patients.
