Risk factors related to early survival after lung transplantation for idiopathic pulmonary fibrosis

VernacularTitle:影响特发性肺间质纤维化患者肺移植术后早期存活率的危险因素分析
Author: Huixing LI ; Yufeng XIE ; Jingyu CHEN ; Mingfeng ZHENG ; Shugao YE ; Feng LIU
Publication Type:Journal Article
Keywords: Lung transplantation; Pulmonary fibrosis; Survival rate
From: Chinese Journal of Organ Transplantation 2014;35(11):658-661
CountryChina
Language:Chinese
Abstract: Objective To estimate the effects of risk factors on early survuval (90 days) after lung transplantation for idiopathic pulmonary fibrosis (IPF).Method We reviewed 49 cases of lung tansplant male patients which suffered from IPF.Two groups were set up according to the early survival.The early outcomes (90 days) were compared between two groups by multiple logistic regression analysis.Result The early survival rate was 81.6％.Multivariate analysis confirmed that mean pulmonary artery pressure and bilateral lung transplantation (BLTx) were risk factors after adjustment for potential confounders.Recipients' age,lung volume reduction on donors,and use of extracorporeal membrane oxygenation (ECMO) were not risk factors for early mortality.Conclusion The increased pulmonary artery pressure and BLTx are risk factors for death after lung transplantation in IPF.Preoperative evaluation of mean pulmonary artery pressure and choosing suitable operative method could improve the surgical outcomes of lung transplantation.