The impact of therapeutic regimen on the depression in type 2 diabetes mellitus: A cross-sectional study
10.3760/cma.j.issn.1000-6699.2015.04.013
- VernacularTitle:治疗方案对2型糖尿病患者抑郁情绪影响的调查研究
- Author:
Bing WU
;
Xuan CHEN
;
Li YANG
;
Fangyuan ZHOU
;
Na CHEN
;
Jing WU
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
Depression;
Insulin;
Oral drugs
- From:
Chinese Journal of Endocrinology and Metabolism
2015;31(4):346-348
- CountryChina
- Language:Chinese
-
Abstract:
To explore the depression in type 2 diabetic patients treated with insulin and compared to those treated with oral anti-diabetic drugs.283 type 2 diabetics were seclected randomly from outpatient and inpatient departments of endocrionology in Jiangsu Province Hospital of Traditional Chinese Medicine,with the self-designed questionnaire and Zung self-rating depression scale to conduct the survey.Comparisons between the two groups were carried out with t-test or x2 test for quantitative and qualitative data,respectively.Logistic regression were used for the analysis of the relationship between the therapeutic regimen and depression.Overall,43.1％ of the type 2 diabetic subjects showed depressive symptoms in different degrees.Compared to the oral drug group,the insulin group showed a significantly higher prevalence of depressive symptoms (insulin group,53.5％,oral drug group,30.5％;P＜0.01)and higher self-rating depression scale scores (insulin group,51.7 ± 12.4,oral drug group,44.8 ± 10.6;P＜0.01).Moreover,after an adjustment for age,sex,body mass index,diabetic duration,complications,HbA1Cand so on,the insulin group showed a significantly higher frequency of depression (OR=4.218,95％ CI 1.764-13.285,P=0.004),compared to the oral drug group.The data showed that insulin treatment is an independent risk factor to the presence of depressive symptoms in type 2 diabetics,and it is necessary to pay more attention to their psychological support.
