Pancreatic neuroendocrine carcinoma: clinicopathological characteristics and prognosis
10.3760/cma.j.issn.1007-631X.2015.05.006
- VernacularTitle:胰腺神经内分泌癌的临床病理特点和预后因素分析
- Author:
Baobao XIN
;
Wenhui LOU
;
Jianang LI
;
Xu HAN
;
Xuefeng XU
- Publication Type:Journal Article
- Keywords:
Pancreatic neoplasms;
Neuroendocrine tumors;
Prognosis;
Neoplasm metastasis
- From:
Chinese Journal of General Surgery
2015;30(5):352-356
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinicopathological characteristics and the related factors influencing the prognosis of pancreatic neuroendocrine carcinoma.Methods The clinicpathological and follow-up data of 21 patients with pancreatic neuroendocrine carcinoma admitted between April 2000 and August 2013 in Zhongshan Hospital of Fudan University were analyzed retrospectively.The influence facts on patients' prognosis were analyzed statistically.Results Univariate analysis showed that age,stage,tumor size,degree of tumor differentiation and lymph node metastasis were factors separately influenced patients' survival.Multivariate analysis (Cox regression) revealed that age (P =0.019) was the only independent factor affecting the prognosis.Conclusions Patients with pancreatic neuroendocrine carcinoma were mostly non-functional and presented no specific clinical features.Tumors tended to metastasize and the prognosis was poor.Age was the independent factor affecting the prognosis.
