Trabeculectomy with Mitomycin C for High Risk Glaucoma : A Comparison between 0.2 and 0.4 mg/ml of Mitomycin C.
- Author:
Kyu Sik KIM
1
;
Jung Il MOON
Author Information
1. Department of Ophthalmology, St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Korea.
- Publication Type:Original Article
- Keywords:
High risk glaucoma;
Mitomycin C;
Trabeculectomy
- MeSH:
Blister;
Cataract;
Glaucoma*;
Hyphema;
Incidence;
Intraocular Pressure;
Mitomycin*;
Rupture;
Trabeculectomy*
- From:Journal of the Korean Ophthalmological Society
2001;42(1):92-97
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
To raise the success rate of trabeculectomy in high-risk glaucomas, surgeons use various concentrations of Mitomycin C(MMC). We have used either 0.2 or 0.4 mg/ml for 4 minutes, so we intended to compare the success rate and complication between the two concentrations. Sixty-three eyes with high risk glaucoma on which MMC trabeculectomy was performed were divided into two groups. MMC concentration of 0.2 mg/ml(32 eyes)was used in the first group and 0.4 mg/ml(31 eyes)in the second group. Intraocular pressure less than 21 mmHg at postoperative 3 months with no treatment or with only one beta-blocker eyedrop application was regarded as success. The success rates showed no statistically significant difference:62.5%in one group and 58.1%in the other(p>0.05). However, the group with treatment of MMC 0.4 mg/ml showed higher incidence of complication such as hypotony, hyphema, leakage, progression of cataract and bleb rupture. In conclusion, MMC concentration of 0.2 mg/ml was safer than 0.4 mg/ml in the view of both success rate and complication development in trabeculectomy of high-risk glaucomas.
