Relationship between thyroid function and serum vitamin D levels in type 2 diabetic patients

VernacularTitle:2型糖尿病患者血清维生素D水平与甲状腺功能的关系研究
Author: Jia LIU ; Yuan XU ; Zhiwei NING ; Li MIAO ; Yanjin HU ; Guang WANG
Publication Type:Journal Article
Keywords: Vitamin D deficiency; Diabetes mellitus,type 2; Thyroid function
From: Chinese Journal of Endocrinology and Metabolism 2015;31(3):245-248
CountryChina
Language:Chinese
Abstract: A total of 180 type 2 diabetic patients with negative anti-thyroid autoantibodies were recruited.According to the levels of serum 25-OH vitamin D [25 (OH) D],these patients were divided into four groups:sufficient group (≥ 30 ng/ml),insufficient group (20-＜30 ng/ml),deficiency group (10-＜20 ng/ml),and severe deficiency group(＜ 10 ng/ml).The results showed that compared with sufficient vitamin D group,the group with severe deficient vitamin D had higher TT3,FT3,FT3/FT4,and TSH (all P＜0.05).The serum 25(OH) D level was negatively correlated with TSH values (r =-0.207,P＜0.05) after adjustment for gender,age,and body mass index.Multivariate regression analysis indicated that serum 25 (OH) D level was an independent influencing factor for TSH value (β =-0.201,P＜0.05),suggesting that serum 25 (OH) D level seems to be correlated with thyroid function in type 2 diabetic patients.