Effect of different meal replacements in patients with metabolic syndrome

VernacularTitle:不同替代膳食模式对代谢综合征患者的影响
Author: Yin HAN ; Yan LIU ; Jieli SHI ; Ruixia LI ; Sufen LI ; Nana JIN ; Honglei GUO
Publication Type:Journal Article
Keywords: Preload fasting; Meal replacement; Metabolic syndrome; Satiety
From: Chinese Journal of Endocrinology and Metabolism 2015;31(3):215-218
CountryChina
Language:Chinese
Abstract: Objective To investigate the impact of preload fasting and meal replacement in patients with metabolic syndrome.Methods A total of 92 subjects with metabolic syndrome were enrolled in the study.They were assigned into the preload fasting group (PFG),the meal replacement group (MRG),and the control group (CG) for 12-weeks intervention.Special dietary with 100 kcal was provided 30 min before each meal in the PFG,and while in the MRG the same dietary was taken just before each meal and the amount of meal was reduced appropriately.The subjects in CG took meals as usual.Body mass index,waist circumference,and insulin resistance were assessed.Satiety situation was investigated by the scale.Results After 12 weeks,improvement were found in fasting insulin(-3.29 mU/L) and waist circumference (-4.04 cm) in the PFG and significant difference was shown compared to the CG (P＜0.05).Satiety index in the PFG was the most significant among the three group.Conclusion Preload fasting is helpful in improving insulin resistance,reducing waist circumference,and enhancing satiety.