A retrospective study of the clinical features in papillary thyroid microcarcinoma
10.3760/cma.j.issn.1000-6699.2015.01.004
- VernacularTitle:甲状腺全切的微小乳头状癌临床特点的回顾性研究
- Author:
Wei ZHENG
;
Jian TAN
;
Guizhi ZHANG
;
Peng WANG
;
Renfei WANG
- Publication Type:Journal Article
- Keywords:
Papillary thyroid cancer;
Microcarcinoma;
Age;
Clinical feature
- From:
Chinese Journal of Endocrinology and Metabolism
2015;31(1):14-17
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify clinical features of papillary thyroid microcarcinoma(PTMC) according to patients' age.Methods Seventy-eight patients with PTMC were divided into 2 groups according to age:≥45 years and <45 years.The clinical data were retrospectively analyzed.Results The average preoperative thyroglobulin (Tg)level in <45 years group was apparently higher than that in ≥45 years group[(138.61 ± 91.87 vs 80.20 ± 85.00) μg/L,P<0.01].The average tumor size in <45 years group was apparently larger than that in ≥45 years group [(0.64 ± 0.24 vs 0.45 ± 0.25) cm,P<0.01].There were more patients with multiple cancer foci in <45 years group than in ≥45 years group (73.53% vs 45.45%,P<0.05).And there were more patients with cancer in bilateral lobes in <45 years group than that in ≥45 years group(44.12% vs 18.18%,P<0.05).There were no significant differences in preoperative thyroid stimulating hormone level,preoperative thyroglobulin antibody (TgAb)level,incidence of capsular invasion of cancer,neck lymph nodes involvement,distant metastasis,and backgrounds of benign thyroid diseases between two groups (all P>0.05).Conclusion The patients with PTMCs had different clinical features according to age.Hence,clinicians should consider an individualized treatment according to age in order to achieve better therapeutic efficacy.