Estrogen, anti-estrogen drugs, and thyroid cancer
10.3760/cma.j.issn.1000-6699.2014.12.019
- VernacularTitle:雌激素及抗雌激素药物与甲状腺癌
- Author:
Xi WANG
;
Zhanjian WANG
- Publication Type:Journal Article
- Keywords:
Estrogen;
Estrogen receptor;
Thyroid cancer;
Anti-estrogen drug
- From:
Chinese Journal of Endocrinology and Metabolism
2014;30(12):1128-1131
- CountryChina
- Language:Chinese
-
Abstract:
Several researches have suggested that estrogen contributes to the initiation and development of thyroid cancer by binding to estrogen receptors (estrogen receptor α,estrogen receptor β,and G-protein-coupled receptor 30),activating gene or non-genomic pathways and regulating proliferation of thyroid cells.Studies on antiestrogen drugs based on inhibiting thyroid cell proliferation may provide a new target in treating thyroid cancer.
