Research progress in cognitive impairment in elderly patients with diabetes mellitus
10.3760/cma.j.issn.1000-6699.2014.10.016
- VernacularTitle:老年糖尿病认知功能障碍的相关研究进展
- Author:
Liyong YANG
;
Ximei SHEN
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus;
Aged;
Cognitive Impairment;
Pathogenesis
- From:
Chinese Journal of Endocrinology and Metabolism
2014;30(10):879-881
- CountryChina
- Language:Chinese
-
Abstract:
Diabetes could damage the peripheral and central nervous system,and was the risk factor of cognitive impairment in the elderly.The pathogenesis of cognitive dysfunction caused by diabetes was complex.At present,hyperinsulinemia and/or insulin deficiency,glycemic control,glycation end-products,inflammatorv mediators,hypothalamic-pituitary-adrenal axis dysfunction,blood-brain barrier dysfunction and other factors were considered to be the major causes of cognitive impairment in elderly patients with diabetes.Good metabolic control may help prevent its occurrence and/or progression.
