Metabolic regulation of brown adipose : a possible new therapeutic approach for metabolic diseases
10.3760/cma.j.issn.1000-6699.2014.10.001
- VernacularTitle:棕色脂肪的调节——针对代谢性疾病的新一代治疗方法探讨
- Author:
Zhenghua XIAO
- Publication Type:Journal Article
- Keywords:
White adipose tissue;
Brown adipose tissue;
Irisin
- From:
Chinese Journal of Endocrinology and Metabolism
2014;30(10):821-825
- CountryChina
- Language:Chinese
-
Abstract:
Browning of white adipose tissue(WAT) is expected to become a possible new therapeutic means for diabetes mellitus and other metabolic diseases in future,because brown adipose tissue (BAT) has attracted scientific interest as an anti-diabetic tissue owning to its ability to dissipate energy as heat.In this article,we reviewed the characteristics of brown fat cells,the major transcription factor and the stimulating factor during browning of WAT,as well as their potential mechanisms and research directions.