New understanding of TSH reference range during the first trimester of pregnancy
10.3760/cma.j.issn.1000-6699.2014.12.001
- VernacularTitle:对妊娠早期TSH参考范围上限值的新认识
- Author:
Weiping TENG
- Publication Type:Journal Article
- Keywords:
Subclinical hypothyroidism;
Pregnancy;
Thyrotropin
- From:
Chinese Journal of Endocrinology and Metabolism
2014;30(12):1039-1040
- CountryChina
- Language:Chinese
-
Abstract:
Guidelines of the American Thyroid Association (ATA) proposed two diagnostic criteria for subclinical hypothyroidism during the first trimester of pregnancy:criterion 1 was based on the pregnancy-specific TSH reference range and criterion 2 on serum TSH＞2.5 mIU/L level with normal serum FT4.According to the results of the Subclinical hypothyroidism during early pregnancy study,author proposed that criterion 2 is not appropriate for Chinese pregnant women because the TSH concentration has become significantly higher in whole Chinese population.By using criterion 2,the prevalence may be as high as 27.8％,which may result in over-diagnosis and over treatment.
