Allergen Specific Serum IgE Antibody in Patients with Intestinal Polyp and Irritable Bowel Syndrome:A Clinical Analysis
10.3969/j.issn.1008-7125.2015.07.009
- VernacularTitle:肠息肉和肠易激综合征患者血清过敏原特异性 IgE 抗体临床分析
- Author:
Guihong WEI
;
Hong JIANG
;
Liping JIANG
;
Jia WANG
- Publication Type:Journal Article
- Keywords:
Intestinal Polyps;
Irritable Bowel Syndrome;
Allergens;
Anaphylaxis
- From:
Chinese Journal of Gastroenterology
2015;(7):421-423
- CountryChina
- Language:Chinese
-
Abstract:
Background:Eosinophilic gastroenteritis is the most common gastrointestinal allergic disease,however,allergy also accounts for some gastrointestinal functional disorders. The correlation between allergic factor and intestinal polyp is not clarified. Aims:To investigate the correlation of allergic factor with intestinal polyp and irritable bowel syndrome(IBS). Methods:Ninety-five inpatients including 60 cases of intestinal polyp and 35 cases of IBS admitted from May 2012 to April 2014 were recruited;95 healthy volunteers were served as controls. Serum samples were collected to test specific IgE antibodies derived from 20 common inhalant and alimentary allergens by EUROIMMUN blotting test. Results:The positivity rates of allergen specific serum IgE antibodies in intestinal polyp group,IBS group and both two groups were 56. 67% ,74. 29% and 63. 16% ,respectively,all were significantly higher than that in control group(6. 32% ,P all <0. 05),but no statistically significant difference was seen between intestinal polyp group and IBS group(P > 0. 05). In all the 20 allergens tested,the positivity rates of Dermatophagoides,roach,crab,sea fish,freshwater fish,shrimp,and egg albumin specific serum IgE antibodies were significantly higher in patients group than in control group( P < 0. 05), especially the crab,see fish and Dermatophagoides specific IgE antibodies. Conclusions:Allergic factor might have some association with intestinal polyp and IBS.
