NO-cGMP-PKG pathway and cardiovascular disease
10.3760/cma.j.issn.1673-4408.2015.04.016
- VernacularTitle:NO-cGMP-PKG通路在心血管疾病中研究进展
- Author:
Binglun ZHANG
;
Chunfeng LIU
- Publication Type:Journal Article
- Keywords:
Cardiovascular diseases;
Signal transduction;
Nitric oxide;
Cyclic GMP
- From:
International Journal of Pediatrics
2015;(4):420-423
- CountryChina
- Language:Chinese
-
Abstract:
Nitric oxide ( NO ) , cyclic guanosine 3′, 5′-monophosphate ( cGMP ) and cGMP-dependent protein kinase( PKG) play an important role in a variety of tissue cells. This paper reviews the related literatures about the NO-cGMP-PKG pathway and the cardiovascular diseases since the close relationship between them by summarizing the founction of the NO-cGMP-PKG pathway and the affection on the cardiovascular diseases by the NO-cGMP-PKG pathway,aiming to find a new research direction of the pathogenesis of cardiovascular disea-ses.
