Survey and analysis of the applicatiaon and compliance of statins in the patients with ischemic stroke
10.3760/cma.j.issn.1673-4904.2014.22.019
- VernacularTitle:缺血性卒中患者他汀类药物治疗依从性调查及原因分析
- Author:
Fei WANG
;
Qinghong LIAO
;
Lili QIN
;
Shili CHEN
;
Wenwen XU
;
Zhiming ZHOU
- Publication Type:Journal Article
- Keywords:
Stroke;
Secondary prevention;
Hydroxymethylglutaryl-CoA reductase inhibitors;
Patient compliance
- From:
Chinese Journal of Postgraduates of Medicine
2014;37(22):60-63
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the application of statins in secondary prevention of ischemic stroke in different risk groups,and to identify the factors influencing the comphcance of statins.Me.ods Ischemic stroke patients from December 2011 to October 2012 were collected.All clinical characterisitcs and possible factors influencing the compliance of statins was recorded in 3 months.The multivariate Logistic regression analysis was used to analyze the influencing factors of the compliance of statins.Results All 368 patients were collected,and 67.9％(250/368) patients were prescribed statins for therapy during hospitalization.The application rate of statins in accordance with guidelines in high-risk,extremely high-risk Ⅱ and extremely high-risk Ⅰ patients was 28.1％ (18/64),44.1％ (30/68) and 72.3％ (136/188),respectively.Logistic regression analysis showed that the statins application during hospitalization was associated with the presence of carotid vulnerable plaques (OR =5.308,P =0.000) and diabetes history (OR =1.789,P =0.032).Routine discharge instructions had high compliance.Conclusion The compliance of statins in secondary prevention of ischemic stroke still has a large gap between clinical practice and guidelines,and routine discharge instructions on statins application increase the compliance of statins.
