Study of non-motor symptoms in early stage newly diagnosed Parkinson's disease
- VernacularTitle:早期初诊帕金森病患者非运动症状的研究
- Author:
Hui XU
;
Weiguo LIU
- Publication Type:Journal Article
- Keywords:
Parkinson's disease;
non-motor symptoms;
clinical subtypes
- From:
Journal of Clinical Neurology
2015;(3):192-194
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical characteristics of non-motor symptoms ( NMS) in early stage newly diagnosed Parkinson 's disease ( PD) patients in different age group and different subtypes .Methods Total 96 newly diagnosed PD patients without taking any drugs and 102 normal controls were collected in outpatient visits , and their clinic information and related scales were evaluated and compared .Results Ninety-one(93.83%) PD patients had at least one NMS, common symptoms were, in order, recent memory (70.83%,68 cases)、constipation (48.96%,47 cases)、attention dysfunction (47.92%,46 cases), and they were significantly higher than PD group (all P<0.01).The incidence of anxiety and panic in patients≤60 years old was significantly higher than that in patients>60 years old (P<0.01).The incidence of urgency in rigidity type was significantly higher than in tremor type(P<0.01).Conclusions NMS in patients with newly diagnosed PD are complex and diverse .The performance in different age groups and different clinical subtypes are also different .