Evaluation of neutrophilic CD64 index and CD32 index as a diagnostic marker of liver cirrhosis with spontaneous bacterial peritonitis in early stage

VernacularTitle:中性粒细胞CD64、CD32指数在肝硬化并自发性细菌性腹膜炎诊断中的价值
Author: Jinhai ZOU ; Xiangjun KONG ; Chunying LI ; Xinyi SUN ; Chendi LIU
Publication Type:Journal Article
Keywords: Liver cirrhosis; Bacterial infection; Neutrophile granulocyte; CD32 index; CD64 index
From: Chinese Journal of Immunology 2015;(6):827-830
CountryChina
Language:Chinese
Abstract: Objective:To investigate the early diagnosis value of neutrophilic CD 64 index(nCD64 ID),neutrophilic CD32 index( nCD32 ID) in ascites and CRP in blood of liver cirrhosis patients combined with spontaneous bacterial peritonitis. Methods:The data of 156 cases with liver cirrhosis was analyzed retrospectively, which CD32 index, CD64 index and CRP were detected respectively and ROC curve analysis were performed. Results:The nCD64 ID,nCD32 ID and CRP in bacterial infection group were all significantly higher than that in no infection group(P<0. 001). The sensitivity and specificity of nCD32 ID,nCD64 ID and CRP were 82. 8%,96. 2%,72. 5% and 81. 0%, 95. 8%, 73. 1% respectively. Conclusion: The sensitivity and specificity of nCD64 ID were higher than nCD32 ID and CRP. The nCD64 ID can be used as an effective index for early diagnosis and differential diagnosis of liver cirrhosis combined with spontaneous bacterial peritonitis.