Etiology of hand foot and mouth disease in Guiyang area during 2012
10.3969/j.issn.1671-8348.2015.14.027
- VernacularTitle:2012年贵阳地区住院患儿手足口病的病原学研究
- Author:
Xinglin YANG
;
Yuedong LIANG
;
Zhangping HONG
;
Jinfeng XIONG
;
Yunfen WANG
;
Jun YAO
;
Hai HUANG
- Publication Type:Journal Article
- Keywords:
hand foot and mouth disease;
enterovirus;
enterovirus A,human;
Coxsackievirus
- From:
Chongqing Medicine
2015;(14):1946-1948
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the pathogen distribution situation among the children inpatients with hand ,foot and mouth diseases(HFMD) in Guiyang area during 2012 to provide the basis for the diagnosis ,treatment and prevention .Methods The data in 3 179 cases of HFMD were collected .The fluorescence quantitative RT‐PCR was adopted to perform the genotyping on universal enterovirus ,enterovirus 71(EV71)and Coxsackie virus A16(CA16) .Results A total 3 179 samples of HFMD were col‐lected ,among them ,151 cases (4 .75% ) were CA16 positive ,331 cases (10 .41% ) were EV71 positive ,7 cases (0 .22% ) were CA16 and EV71 co‐infection ,and 897 cases(28 .22% )were the other enterovirus .The whole year had 2 peaks of onset ,which were April to July and October to November .The onset age focused on the children aged under 5 years old (96 .16% ) ,among them ,0-3 years old had the highest onset ,moreover male children were more than female .Conclusion The etiology distribution of children HFMD in Guiyang area during 201 was dominated by the other genotypes of enterovirus and EV71 .
