Synthesis and anti-fungal and antibiotic activities of chlorothioure derivatives
- Author:
Phuong Truong
- Publication Type:Journal Article
- Keywords:
chlorothioure
- MeSH:
Antifungal Agents;
Anti-Bacterial Agents;
Drug Compounding
- From:Pharmaceutical Journal
2001;306(10):14-18
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Condensation of 4-chlorophenylisocyanat with amine compounds (p-amino salicylic acide, phenyl hydrazine derivatives) gets 7 thiourea derivatives. The structures of the obtained products were determined by elemental analysis and IR spectroscopy. The study indicated that all of them have strong effect on bacteris Gram(+) but weak on GR(-). Six compounds have affected on Microsporum gypseum and Tricophyton mentagrophytes. Two compounds have effects on Candida albicans.
