Content Comparison of Polydatin and Emodin between Polygonum Cuspidatum Pieces and Dispensing Gran-ules
- VernacularTitle:虎杖饮片及其配方颗粒中虎杖苷和大黄素的含量比较
- Author:
Dong XIA
;
Sun YING
- Publication Type:Journal Article
- Keywords:
Polygonum cuspidatum;
Dispensing granules;
Polydatin;
Emodin;
Content determination
- From:
China Pharmacist
2015;(6):1060-1062
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the content of polydatin and emodin between polygonum cuspidatum pieces and dispensing gran-ules to provide theoretical basis for the improvement of preparation process of the granules. Methods:An HPLC method with linear gra-dient elution was used to determine the content of polydatin and emodin in the pieces and dispensing granules, and the difference in the two contents was compared. Results: The content of polydatin and emodin in polygonum cuspidatum pieces met the requirement de-scribed in China pharmacopoeia, which was lower than that in the dispensing granules, and the contents of the two components in the commercial dispensing granules were not equivalent to the labeled amount, which was 1/15 and 1/27 of that in the pieces. Conclu-sion:The transport rate of the traditional preparation process of dispensing granules is with poor efficiency, which should be improved.
