Research progress of transforming astrocytes into neurons
10.11958/j.issn.0253-9896.2015.06.031
- VernacularTitle:星形胶质细胞转分化为神经元的研究进展
- Author:
Wenbo KANG
;
Sai ZHANG
;
Haiqian LIANG
- Publication Type:Journal Article
- Keywords:
cell tranformation;
neurons;
astrocytes
- From:
Tianjin Medical Journal
2015;(6):694-697
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, the rapid development of stem cell transforming technology and regeneration pose great re?search value. With maturation of transformation induction, other cell lineages were shown to be able to transform into neu?rons. In addition, astrocytes are widely distributed in the gray and white matter of the central nervous system, whose exces?sive proliferation contribute to glial fibrillary scar formation, which is the key obstacle in recovery of neurological function. Therefore, the study of transforming astrocytes into neurons draw attention from many scientists. Astrocytes transformation not only prevent the formation of glial scar, but also generate new neurons. This article summarized relevant studies that re?port function of astrocytes and its transformation into neurons.
