The Prognostic Effect of Left Ventricular End-diastolic Pressure During Primary Percutaneous Coronary Intervention in Patients With Acute ST-segment Elevation Myocardial Infarction
10.3969/j.issn.1000-3614.2015.06.008
- VernacularTitle:左心室舒张末期压力对行介入治疗的急性ST段抬高型心肌梗死患者的预后价值
- Author:
Jingjing JIA
;
Pingshuan DONG
;
Laijing DU
;
Zhijuan LI
;
Ximei FAN
;
Honglei WANG
;
Xishan YANG
;
Xuming YANG
- Publication Type:Journal Article
- Keywords:
Left ventricular end-diastolic pressure;
ST-segment elevation myocardial infarction;
Mortality
- From:
Chinese Circulation Journal
2015;(6):543-546
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the post-operative mortality of left ventricular end-diastolic pressure (LVEDP) during primary percutaneous coronary intervention (PCI) in patients with acute ST-segment elevation myocardial infarction (STEMI). Methods: We retrospectively analyzed 255 patients with new onset of STEMI who received primary PCI in our hospital and all patients received LVEDP measurement before coronary artery opening. According to LVEDP value, the patients were divided into 2 groups: LVEDP≤14 mmHg group,n=155 and LVEDP>14 mmHg group,n=100. The post-operative mortality up to 6 months was observed, and the effect of LVEDP on death rate was studied by Cox regression analysis. Results: Compared with LVEDP≤14 mmHg group, the patients in LVEDP>14 mmHg group had the 6 months mortality at HR=4.26, 95% CI (1.13-16.08),P=0.03. Relevant study presented that LVEDP was slightly related to LVEF (r=-0.267, P=0.001) and BNP (r=-0.154,P=0.041). Multi-regression analysis indicated that with adjusted LVEF and BNP, LVEDP was the independent predictor for post-operative mortality up to 6 months in acute STEMI patients after PCI. Conclusion: The LVEDP value measured during PCI procedure is the independent predictor for mortality after PCI in patients with new onset of STEMI.
