Comparative Study of Thymosin α1 Combining Anti-coagulation Medication and Simple Anti-coagulation Medication for Treating the Patients With Deep Venous Thrombosis Formation

VernacularTitle:胸腺肽α1结合抗凝与单纯抗凝治疗深静脉血栓形成的对比研究
Author: Hongzhi SUN ; Xinjun LI
Publication Type:Journal Article
Keywords: Deep venous thrombosis; Deep venous thrombosis formation; Thymosin α1; Immunological regulation
From: Chinese Circulation Journal 2015;(6):556-558
CountryChina
Language:Chinese
Abstract: Objective: To compare the therapeutic effect of thymosin α1 combining anti-coagulation medication and simple anti-coagulation mediation in treating the patients with deep venous thrombosis (DVT) formation. Methods: A total of 92 patients with lower extremity vascular ultrasound conifrmed diagnosis of DVT were studied. The patients were randomly divided into 2 groups for treatment: Combination group, the patients received thymosin α1 combining anti-coagulation medication,n=45 and Simple group, the patients received only anti-coagulation medication,n=47. The changes of their deep venous thrombosis condition after treatment were compared between 2 groups. Results: By 4 weeks treatment, the proportion of completely dissolved thrombus in Combination group and in Simple group were 67 branches (49.26%) and 54 branches (37.24%); the thrombus progression and recurrence condition were 6 branches (4.41%) and 16 branches (11.03%), allP<0.05. Conclusion: Thymosin α1 combining anti-coagulation medication has the better effect than simple anti-coagulation medication for treating DVT patients.